CRISPR/Cas9 analysis of essential genes
Project Description

The CRISPR/Cas9 technology has revolutionised the ability to perform gene editing including gene knockout in mammalian cells. Knockout of genes essential for cell growth, however, is not possible using CRISPR/Cas9 alone. This project involves the use of inducible systems to disrupt essential genes and study their functions in cancer cells.

Supervisor
POON Randy Yat Choi
Co-Supervisor
MA, Hoi Tang
Quota
2
Course type
UROP1000
UROP1100
UROP2100
UROP3100
Applicant's Roles

• Design and conduct experiments
• Analysis and presentation of data

Applicant's Learning Objectives

• Be proficient in techniques in molecular and cell biology
• Develop ability to analyse results and trouble shooting
• Develop team work

Complexity of the project
Challenging