Functions of Mitochondria in Huntington's Disease Mouse Model
Project Description

Many neurodegenerative diseases show abnormal mitochondrial morphology and biochemical dysfunction. It is unclear whether there is any abnormalcy of mitochondria caused by mutant Huntingtin protein in Huntington's disease. We are investigating whether there is any defect in mitochondria in our Huntington's disease mouse model.

Supervisor
PARK Hyo Keun
Co-Supervisor
PARK, Hyo Keun
Quota
1
Course type
UROP1000
UROP1100
UROP2100
UROP3100
UROP4100
Applicant's Roles

Testing whether mutant Huntingtin proteins disrupt the functions of mitochondria in
Huntington's disease mouse model by measuring the size and number of mitochondria.

Applicant's Learning Objectives

Learning how to solve the important biological questions.

Complexity of the project
Challenging