Investigating synaptic transmission in Alzheimer's disease
Project Description

Synaptic transmission in Alzheimer's disease is a crucial question but remain elusive. In order to address this question, we will study how synaptic vesicles are release in neurons with amyloid. We will figure out how amyloid affect the exocytosis of synaptic vesicles.

Supervisor
PARK Hyo Keun
Quota
2
Course type
UROP1000
UROP1100
UROP2100
UROP3100
UROP4100
Applicant's Roles

1. Read the papers related to Alzheimer's disease
2. Dissociate hippocampal neurons.
3. Perform the assay of synaptic vesicles in the presence of amyloid.

Applicant's Learning Objectives

1. Students will learn the current issues of Alzheimer's disease
2. Students will have a hand-on experience.

Complexity of the project
Moderate