Membraneless organelles are compartments in the cell that allow dynamic assembly of biomacromolecules to undergo important biochemical reactions. Liquid-liquid phase separation, which is the underlying physical phenomenon, is facilitated by the non-covalent assembly of intrinsically disordered proteins (IDP). This project is about designing and preparing materials to imitate IDP, followed by characterization of phase behaviour in different environments.
-Assist in the preparation of IDP-like materials
-Characterize the IDP-like materials
-Analyse the thermodynamics parameters related to phase separation
-learn basics of polymer and peptide synthesis
-apply thermodynamics principles in understanding biomaterials behaviour