UROP Project Listing System
Project Title:
CRISPR/Cas9 analysis of essential genes
Supervisor:POON Randy Yat Choi
Co-Supervisor:MA Hoi Tang
Project Description:The CRISPR/Cas9 technology has revolutionised the ability to perform gene editing including gene knockout in mammalian cells. Knockout of genes essential for cell growth, however, is not possible using CRISPR/Cas9 alone. This project involves the use of inducible systems to disrupt essential genes and study their functions in cancer cells.
Course type: UROP1100 UROP2100 UROP3100 UROP4100 
Applicant's Roles:• Design and conduct experiments • Analysis and presentation of data 
Applicant's Learning Objectives:• Be proficient in techniques in molecular and cell biology • Develop ability to analyse results and trouble shooting • Develop team work 
Complexity of the project:Challenging 

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