The CRISPR/Cas9 technology has revolutionised the ability to perform gene editing including gene knockout in mammalian cells. Knockout of genes essential for cell growth, however, is not possible using CRISPR/Cas9 alone. This project involves the use of inducible systems to disrupt essential genes and study their functions in cancer cells.
UROP1100 UROP2100 UROP3100 UROP4100
• Design and conduct experiments
• Analysis and presentation of data
Applicant's Learning Objectives:
• Be proficient in techniques in molecular and cell biology
• Develop ability to analyse results and trouble shooting
• Develop team work